Warning really should be exercised when administering Promethazine to pediatric clients two decades of age and more mature. It is usually recommended that the lowest successful dose of Promethazine be Utilized in pediatric sufferers 2 a long time of age and more mature and concomitant administration of other drugs with respiratory depressant consequences be avoided. WARNINGS

The typical helpful dose of Promethazine for that Energetic therapy of nausea and vomiting in children or adults is twenty five mg.

Pediatric people need to be supervised in order to avoid possible harm in bike riding or in other hazardous functions.

Avoidance and control of nausea and vomiting connected with specific different types of anesthesia and surgical procedures.

Promethazine HCl Oral Option should be employed cautiously in individuals with heart problems or with impairment of liver function.

Prescription drug abuse is the intentional non-therapeutic usage of a prescription drug, even at the time, for its satisfying psychological or physiological outcomes.

In the event the affected person develops these symptoms or signs, raise the dose to the previous degree and taper far more slowly and gradually, either by growing the interval amongst decreases, decreasing the quantity of transform in dose, or both of those.

Recommend sufferers to always use an precise milliliter measuring machine when measuring and administering Promethazine HCl and Codeine Phosphate Oral Remedy. Advise sufferers that a house teaspoon is not an correct measuring machine and this kind of use could lead on to overdosage and really serious adverse reactions [see Overdosage (ten)].

Warning should be exercised when administering Promethazine HCl Oral Solution to pediatric patients 2 a long time of age and more mature as a result of possible for deadly respiratory depression. Respiratory depression and apnea, in some cases connected with Loss of life, are strongly affiliated with Promethazine goods and therefore are not directly relevant to individualized pounds-primarily based dosing, which could or else allow Secure administration.

Asthma Together with other Respiratory Problems: Narcotic analgesics or cough suppressants, which include codeine, should not be Utilized in asthmatic patients (see CONTRAINDICATIONS). Nor should really they be used in acute febrile health issues associated with successful cough or in Serious respiratory condition where interference with ability to crystal clear the tracheobronchial tree of secretions would've a deleterious effect on the client’s respiratory function.

While antihistamines are already observed to supply fetal mortality in rodents, the pharmacological consequences of histamine inside the rodent do not parallel Those people in gentleman. There are no satisfactory and perfectly-managed reports of Promethazine HCl Oral Answer in pregnant Ladies.

Overdose of codeine in adults continues to be connected to fatal respiratory depression, and the use of codeine in children more youthful than twelve years of age has become associated with deadly respiratory depression when used as suggested [see Warnings and Precautions (five.

Appropriate evaluation of the individual, good prescribing methods, periodic re-analysis of therapy, and appropriate dispensing and storage are correct measures that help to limit abuse of opioid prescription drugs.

Promethazine is effectively absorbed with the gastrointestinal tract. Medical consequences are evident within 20 minutes just after oral administration and usually previous four to six hrs, Despite the fact get more info that They might persist provided that twelve hrs.